Product introduction

Actilyse 50mg Injection is a medicine which dissolves the clots that have formed in blood vessels. It is used to treat stroke, heart attack, and pulmonary embolism (blood clots in the lungs). It is known as a thrombolytic or “clot-busting” medicine.

Actilyse 50mg Injection is given directly into a vein by a doctor as soon as possible after the first signs of a heart attack, stroke, or pulmonary embolism are noticed. Your breathing, blood pressure, oxygen levels and other vital signs will be watched closely. You may be given another medicine to prevent the formation of new blood clots at the same time or after the treatment.

Actilyse 50mg Injection may cause confusion, nausea, and vomiting. It has many serious side effects. The most common and serious side effect of this medicine is bleeding. Treatment with this drug can lead to bleeding in the brain (cerebral hemorrhage), extremely low blood pressure (shock), and cardiac arrest (where your heart stops beating). Your treatment may be stopped if any of these happen. Talk to your doctor about the risk of serious side effects before you are given this medicine.

This medicine is not suitable for everyone. There is a long list of situations where you will not be given Actilyse 50mg Injection including if you have had a head injury, surgery of your brain or spinal cord, and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.

Uses of Actilyse Injection

Treatment of Heart attack
Treatment of Ischemic stroke
Treatment of Pulmonary embolism

Benefits of Actilyse Injection

In Treatment of Heart attack

Actilyse 50mg Injection dissolves harmful blood clots that cause heart attack (if they are in the heart). They also dissolve clots that form in other blood vessels. This means that blood can again start to flow freely through your body. This medicine will, therefore, reduce both the damage caused by, and the risk of dying from a heart attack. The sooner the injection is given, the greater are the chances of recovery.

Side effects of Actilyse Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actilyse

Bleeding
Nausea
Vomiting
Confusion

How to use Actilyse Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Actilyse Injection works

Actilyse 50mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actilyse 50mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Actilyse 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Actilyse 50mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

NOT RELEVANT

Not relevant, as Actilyse 50mg Injection is intended for use in hospitalised patients.

Kidney

SAFE IF PRESCRIBED

Actilyse 50mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Actilyse 50mg Injection may not be needed in these patients. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Actilyse 50mg Injection in patients with liver disease. Please consult your doctor.